By Peter S. Harper
An eminent geneticist, veteran writer, OMMG sequence Editor, and famous archivist, Peter Harper provides a full of life account of the way our rules and information approximately human genetics have constructed during the last century from the viewpoint of somebody contained in the box with a deep curiosity in its historic points. Dr. Harper has researched the background of genetics and has had own touch with a number of key figures whose thoughts and reviews expand again 50 years, and he has interviewed and recorded conversations with a lot of those very important geneticists. hence, instead of being a traditional background, this booklet transmits the essence of the tips and the folk concerned and the way they interacted in advancing- and infrequently retarding- the sector. From the origins of human genetics; during the contributions of Darwin, Mendel, and different giants; the id of the 1st human chromosome abnormalities; and up during the of completion of the Human Genome undertaking, this Short History is written within the author's attribute transparent and private sort, which appeals to geneticists and to all these drawn to the tale of human genetics.
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Additional info for A Short History of Medical Genetics
It is unlikely that this was the result of any conscious or speciﬁc restriction related to his being based in a monastic setting; rather, the policy of his order and its enlightened abbot, Cyrill Knapp, was to place his religious community at the forefront of agricultural improvement and scientiﬁc thought for the beneﬁt of the local population. Even so, Abbot Knapp had to ﬁght political battles to maintain such a liberal course, and involvement in topics such as human heredity would not have been helpful in this endeavor, nor would it have been of practical signiﬁcance.
I suspect that it has also played a valuable role in keeping medical geneticists in close contact with basic scientists working on experimental species such as the mouse and Drosophila. Science historians might ﬁnd this an interesting topic to analyze further. Early Concepts of Heredity It is not surprising that questions surrounding human heredity were debated from the earliest times, even though it was not until the 17th century that a truly scientiﬁc approach began to be taken. The Greeks took a keen interest in matters of human reproduction, such as sex determination, the reasons for familial likeness, and external inﬂuences possibly causing congenital malformation.
Exactly this had happened when, in 1844, Robert Chambers, an Edinburgh publisher, had anonymously written and published Vestiges of the Natural History of Creation, which presented an evolutionary basis for life with a number of remarkably prescient speculations but with no rigorous evidence base. The resulting furor did Darwin a favor by opening up the topic of evolution as ﬁt for discussion, drawing down much of the emotional reaction that would otherwise have later descended on Darwin in full force.
A Short History of Medical Genetics by Peter S. Harper