By Charles M. Poser
This illustrated pocketbook provides an simply available precis of key matters with regards to diagnosing a number of sclerosis and coping with sufferers at assorted levels of the disease.
summary: This illustrated pocketbook offers an simply available precis of key matters when it comes to diagnosing a number of sclerosis and handling sufferers at diverse levels of the ailment
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Extra resources for An illustrated pocketbook of multiple sclerosis
Coomassie brilliant blue stain. Courtesy of Dr James Faix, Beth Israel Deaconess Medical Center, Boston, MA present and none in the serum. The presence of oligoclonal bands in the CSF is not specific for MS; they may be noted in other conditions. They never disappear from the CSF in MS, but may do so in disseminated encephalomyelitis. Evoked potential studies Pattern-reversal visual evoked responses are particularly useful in identifying optic nerve and chiasmatic lesions in patients who have had no symptoms or signs of involvement of the visual system, because they may be delayed in 75% of such patients, including those with normal visual acuity.
There are no MRI patterns of ‘lesions’, including the ovoid periventricular lesion, which are essential or even diagnostic of MS. , (2001) criteria were derived retrospectively from the images of patients who had had a clinically isolated syndrome who then had a second episode and thus were deemed to have MS. A very important, but rarely emphasized, use of MRI is in the routine visualization of the cervical cord. In a surprisingly large number of MS patients, cervical cord plaques can be seen adjacent to areas of compression—whether actual, potential or intermittent—by spondylosis and/or herniated disks (Figures 40– 42).
Because Figure 28 Visual evoked response in a patient with left optic atrophy. The P1OO wave on the left is delayed compared with that on the right. Courtesy of Dr Frank Drislane, Beth Israel Deaconess Medical Center, Boston, MA the response is modified by changes in visual acuity, it is imperative that the patient wears prescribed corrective lenses during the test. Delay in P100 is far from specific for MS lesions of the optic system; in addition to poor fixation and changes in 48 AN ILLUSTRATED POCKETBOOK OF MULTIPLE SCLEROSIS Figure 29 Audiogram (upper) showing acute partial hearing loss in left ear, specifically, hearing loss at high frequencies; (lower) the brain stem auditory evoked response shows delay of waves 11 and V in the left ear.
An illustrated pocketbook of multiple sclerosis by Charles M. Poser